Testosterone: Testosterone time-released pellets are bio-identical hormones. They have been used by many women to increase energy levels, increase sex drive, elevate mood, and strengthen bones. They can also help relieve menopausal symptoms. Side-effects can include acne, oily skin, facial hair growth, irritability, headache, nausea, and irreversible male pattern baldness and deepening of the voice. Testosterone can also cause birth defects and should not be used in women who are pregnant or could become pregnant.

Estrogen: Estrogen time-released pellets are bio-identical hormones. They have been used by many women to relieve menopausal symptoms, including, hot flashes, night sweats, and vaginal dryness. They can also help strengthen bones. Side-effects can include breast tenderness, bloating, and headache. If a woman has a uterus, she will need to use progesterone to protect the uterine lining from overstimulation.

Pellets should not be used in patients with a personal history of breast cancer or blood clots.

Pellets are inserted under the skin using a local anesthetic. The incision is very small and needs only a steri-strip to help with closure. Irritation is common at the incision site. Rarely, the pellet insertion site may become infected. The effects of pellets usually last for 2-3 months, but can last up to 6 months.


Absolute contraindications

  • Undiagnosed vaginal bleeding
  • Severe liver disease
  • Pregnancy
  • Coronary artery disease (CAD)
  • Venous thrombosis
  • Well-differentiated and early endometrial cancer (once treatment for the malignancy is complete, is no longer an absolute contraindication.) Progestins alone may relieve symptoms if the patient is unable to tolerate estrogens.

Relative contraindications 

  • Personal history of breast cancer
  • Personal history of uterine cancer
  • Atypical ductal hyperplasia of the breast
  • Active gallbladder disease
  • Heart disease

For more information call our office for a consultation with a provider.